The ALS-associated co-chaperone DNAJC7 mediates neuroprotection against proteotoxic stress by modulating HSF1 activity
Amyotrophic Lateral Sclerosis (ALS) is a devasting neurodegenerative disease which is driven by the dysfunction and degeneration of upper and lower motor neurons (MNs)1,2. The progressive loss of MNs leads to muscle atrophy and diminished ability to …